郭秋岩,张彦琼,林娜.中医药干预神经病理性疼痛的作用机制研究进展[J].,2017,4(11):1-6.
中医药干预神经病理性疼痛的作用机制研究进展
Mechanism progress of traditional Chinese medicine on the treatment of neuropathic pain
投稿时间:2017-05-05  最后修改时间:2017-06-02
DOI:
中文关键词:  神经病理性疼痛;中药单体;中药复方;作用机制
英文关键词:neuropathic pain; monomer of traditional Chinese medicine; Chinese formulae; mechanism
基金项目:
作者单位E-mail
郭秋岩 中国中医科学院中药研究所 reborn528866@126.com 
张彦琼 中国中医科学院中药研究所 yqzhang@icmm.ac.cn 
林娜 中国中医科学院中药研究所  
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中文摘要:
      【】神经病理性疼痛是一种发病机制复杂的难治性疾病,目前的主要治疗手段是药物干预。由于西药存在着镇痛作用有限、副作用明显、价格昂贵等局限性,促使越来越多的神经病理性疼痛患者试图寻求中医药手段缓解症状、改善病情和提高生命、生活质量。中医注重整体观和辨证论治思想的指导下用药,对患者进行整体调理,中药具有多成分、多靶点、多途径发挥作用的特点,中医药在治疗神经病理性疼痛方面具有独特的优势。本综述通过分别在中国知网和Pubmed数据库检索近年来中医药治疗神经病理性疼痛的文献报道,总结中医药治疗神经病理性疼痛的理论基础,汇总中药单体(包括植物药、动物药和矿物药)、中药复方和中医非药物手段治疗神经病理性疼痛的作用机制,为神经病理性疼痛的临床安全、合理用药及新药研发提供参考依据。
英文摘要:
      Neuropathic pain (NP) is one of the most difficult type of chronic pain to manage with its complex pathogenesis, and it''s mainly intervened by chemical drugs. Due to the limitations of unsatisfied analgesic effects, obvious side effects and high price, an increasing number of NP patients try to seek traditional Chinese medicine (TCM) or other methods to relieve symptoms, ameliorate the condition of health and improve the quality of life and living. TCM characterized by multiple components, multiple targets and holistic regulation, has been widely utilized in clinics for centuries. In this paper, we screened papers mentioned mechanisms of TCM on the treatment of NP from CNKI and Pubmed. By literature analysis, we concluded mechanisms of monomer of TCM which include plants, animals and mineral drugs , Chinese formulas and non-drug methods of TCM on the treatment of NP, so as to providing reference for rational administration and drug development.
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